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Related Experiment Videos

[Systemic vascular reactions to a decrease in volumetric blood flow velocity during artificial circulation]

V V Orlov, L I Osadchiĭ, A P Pugovkin

    Fiziologicheskii Zhurnal SSSR Imeni I. M. Sechenova
    |January 1, 1982
    PubMed
    Summary

    Reduced blood flow causes neurogenic constriction in weakly pulsating flow, unlike pulsating flow where myogenic responses compensate. These effects are notable at high systemic perfusion pressure.

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    [Systemic errors in the estimation of systemic arterial pressure via transfer functions after experimental changes of the circulating blood volume].

    Patologicheskaia fiziologiia i eksperimental'naia terapiia·2017

    Area of Science:

    • Physiology
    • Cardiovascular Research
    • Hemodynamics

    Context:

    • Investigates the regulation of systemic hemodynamics in anesthetized cats under artificial circulation.
    • Examines the effects of reduced blood flow volume velocity on systemic perfusion pressure (SPP).

    Purpose:

    • To elucidate the distinct vascular responses to reduced blood flow under different flow pulsation conditions.
    • To understand the role of neurogenic and myogenic mechanisms in regulating vascular tone.

    Summary:

    • A decrease in systemic perfusion pressure (SPP) from reduced blood flow velocity triggers a neurogenic constrictory response in weakly pulsating blood flow.
    • This neurogenic response can be counteracted by a myogenic response in pulsating blood flow, particularly at high initial SPP levels.

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  • The myogenic component of resistance vessel tonus regulation appears suppressed during weakly pulsating blood flow.

    • Impact:

    • Highlights the differential regulation of vascular tone based on blood flow characteristics.
    • Provides insights into the mechanisms governing systemic hemodynamics and potential implications for circulatory control.