Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Temporary threshold shift modified by binaural acoustic stimulation

A R Cody, B M Johnstone

Hearing Research

|February 1, 1982

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The use of conventional antipsychotic medications for patients with schizophrenia in a medicaid population: therapeutic and cost outcomes over 2 years.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2006

Same author

Designing naturalistic prospective studies of economic and effectiveness outcomes associated with novel antipsychotic therapies.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·2006

Same author

Use of conventional antipsychotics and the cost of treating schizophrenia.

Health care financing review·2002

Same author

Human papillomavirus as a risk factor for oral squamous cell carcinoma: a meta-analysis, 1982-1997.

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics·2001

Same author

Olanzapine versus risperidone. A prospective comparison of clinical and economic outcomes in schizophrenia.

PharmacoEconomics·2001

Same author

Antipsychotic drug use patterns and the cost of treating schizophrenia.

Psychiatric services (Washington, D.C.)·2000

Contralateral acoustic stimulation at the same frequency reduces hearing loss from intense sounds. This protective effect, mediated by auditory efferents, is frequency-specific and blocked by strychnine.

Area of Science:

Neuroscience
Auditory Neuroscience
Otoacoustic Emissions

Background:

Intense sound exposure can cause temporary or permanent hearing loss.
The auditory system possesses efferent pathways that modulate sensory input.

Purpose of the Study:

To investigate the protective role of contralateral acoustic stimulation against ipsilateral noise-induced hearing loss.
To determine the frequency specificity and neural mechanisms underlying this protective effect.

Main Methods:

Monaural exposure to an intense pure tone.
Simultaneous contralateral acoustic stimulation at varying frequencies.
Administration of strychnine to block auditory efferent activity.

Main Results:

Related Experiment Videos

Contralateral stimulation at the same frequency as the ipsilateral trauma significantly reduced hearing sensitivity loss.
This protective effect was abolished when the contralateral stimulus frequency differed from the ipsilateral trauma frequency.
Strychnine administration eliminated the reduction in hearing sensitivity loss.

Conclusions:

Acoustic activation of the auditory efferent system provides a protective mechanism against noise-induced hearing loss.
This efferent-mediated protection is frequency-specific.
Auditory efferents play a crucial role in modulating cochlear sensitivity and preventing acoustic trauma.