[Human optic nerve head lesions in the aged (author's transl)]

Area of Science:

• Ophthalmology
• Gerontology
• Pathology

Context:

• Age-related changes in the optic nerve head are common but require detailed characterization.
• Previous preliminary studies identified specific senile degenerative lesions.

Purpose:

• To determine the frequency, localization, and timing of two specific senile degenerative lesions in the aged human optic nerve head.
• To present frequency curves and compare findings with existing literature.

Summary:

• Examined 109 human optic nerve heads from aged individuals.
• Analyzed the occurrence, anatomical location, and onset of two types of senile degenerative lesions.
• Generated frequency curves and discussed results in context with published data.

Impact:

• Provides crucial data on the prevalence and characteristics of age-related optic nerve head pathologies.
• Contributes to a better understanding of normal aging processes affecting vision.
• Informs future research on age-related visual impairments and potential interventions.