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Age changes in human vocal muscle

T Sato, H Tauchi

    Mechanisms of Ageing and Development
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Vocal muscle aging in Japanese males shows fiber number decreases after 50. Red fibers increase in volume with age, while white fibers do not.

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    Area of Science:

    • Gerontology
    • Muscle physiology
    • Histology

    Background:

    • Vocal muscle function is crucial for communication.
    • Age-related changes in muscle tissue can impact function.
    • Understanding vocal muscle senescence is important for healthspan.

    Purpose of the Study:

    • To investigate age-related microscopic changes in vocal muscle fibers.
    • To differentiate between senile changes in red and white muscle fibers.

    Main Methods:

    • Micromeasuring studies on 109 Japanese males (aged 18-97).
    • Paraffin sections stained with phosphotungstic-hematoxylin for fiber differentiation.
    • Analysis of fiber number and volume changes with age.

    Main Results:

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    • Overall decrease in vocal muscle fiber number after age 50.
    • Both red and white fibers showed a slight increase in volume with age.
    • White fibers decreased significantly in number earlier and showed no volume increase.
    • Red fibers exhibited a significant decrease in number and a significant volume increase after age 80.

    Conclusions:

    • Vocal muscle aging involves differential changes in red and white fiber populations.
    • Red fibers may compensate for loss through hypertrophy, while white fibers show decline.
    • These findings contribute to understanding vocal aging and potential interventions.