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[Rheo- and electroencephalographic studies in transient cerebral circulatory disorders]
Insights
Transitory cerebral circulation disturbances show lasting changes in cerebral hemodynamics, even after neurological symptoms resolve. This highlights that "transitory" mainly describes clinical recovery, not full physiological normalization.
Area of Science:
- Neurology
- Neurophysiology
- Medical Imaging
Context:
- Investigated patients with transitory cerebral circulation disturbances (TCD) and healthy controls.
- Utilized dynamic rheoencephalography (REG) and electroencephalography (EEG) for comprehensive assessment.
- Examined REG parameters including amplitude, anacrotism duration, dicrotic index, and hemispheric blood flow.
Purpose:
- To compare bioelectric brain activity (EEG) with cerebral blood flow (REG) in patients with TCD.
- To dynamically analyze the persistence of hemodynamic changes after TCD symptom resolution.
- To evaluate the relationship between cerebral blood flow and brain function in TCD patients.
Summary:
- EEG and REG data revealed an interdependence and parallelism between bioelectric activity and cerebral blood flow.
- Pathological changes in cerebral blood flow were found to persist long after neurological symptoms subsided.
- This suggests that "transitory" in TCD primarily reflects clinical symptom evolution, not complete hemodynamic recovery.
Impact:
- Challenges the notion of complete recovery in TCD, emphasizing prolonged hemodynamic alterations.
- Provides evidence for the long-term impact of TCD on cerebral hemodynamics.
- Informs clinical understanding and management of patients following TCD events.
Abstract:
Dynamic examinations of 83 patients with transitory cerebral circulation disturbances and 40 healthy subjects (control group) were carried out in clinical conditions. Rheoencephalograms were recorded using frontomastoid, bitemporal, and bimastoid leads. Electroencephalograms were recorded on a 12-channel electroencephalograph. The EEGs were recorded within a period from the 8th to the 15th day since the appearance of the transitory neurological symptoms, while the REGs were registered within a year after the subsidence of the transitory disturbances. The following REG parameters were analyzed: amplitude, anacrotism duration (in seconds and per cent) dicrotic index, time of rheographic wave spreading, hemispheric circulation time, hemispheric blood flow. A comparison of the bioelectric activity changes with the cerebral flow level calculated from the REG data pointed to an interdependence of both parameters and a parallelism in their changes. This could be explained by retention of the relations between the blood flow and the cerebral functions in the patients with the transitory cerebral circulation disturbances. A dynamic analysis of the quantitative REG parameters showed that the pathological changes of the cerebral blood flow persisted for a long time after the subsidence of the transitory disturbances of the cerebral circulation and normalization of the neurological status. This is an evidence of the relative character of the notion transitory cerebral circulation disturbances which reflects only the evolution of the clinical manifestations, but ignores the duration of the changes in the cerebral hemodynamics.