Postprandial effects of dietary phosphatidylcholine on plasma lipoproteins in man

To evaluate the effects of dietary phospholipids on plasma lipoproteins in the postprandial phase six normolipidemic men were fed alternatively a test meal rich in phosphatidylcholine and a control meal low in phosphatidylcholine. Plasma very low-density lipoproteins, low-density lipoproteins, and high-density lipoproteins were isolated at 2, 4 and 6 h after the meals. The changes in lipoprotein cholesterol, triacylglycerol, and phospholipid after feeding the phospholipid-rich meal were indistinguishable from those after the low-phospholipid meal. The phospholipid composition in high-density lipoproteins was also unchanged. The amount of phosphatidylcholine used in this trial was approximately 10-fold higher than that found in the normal Swedish diet. It is therefore concluded that the normal dietary intake of phosphatidylcholine has little influence on the plasma lipoprotein parameters measured in the present study.