Related Experiment Video

Updated: Jul 11, 2026

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
14:19

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction

Published on: June 29, 2013

Intrauterine growth retardation: a study of long-term morbidity

J A Low, R S Galbraith, D Muir

    American Journal of Obstetrics and Gynecology
    |March 15, 1982
    PubMed

    Insights

    Children with intrauterine growth retardation (IUGR) showed similar developmental outcomes to peers, despite being smaller. Socioeconomic status significantly impacted motor and cognitive deficits in these children.

    Area of Science:

    • Pediatrics
    • Developmental Psychology
    • Public Health

    Background:

    • Intrauterine growth retardation (IUGR) affects fetal development, potentially impacting long-term health and development.
    • Previous research indicates varied outcomes for IUGR children, necessitating longitudinal studies.
    • Understanding developmental trajectories is crucial for early intervention and support.

    Purpose of the Study:

    • To assess the long-term motor, cognitive, and language development of children born with IUGR.
    • To compare developmental outcomes between IUGR children and those with appropriate birth weight.
    • To identify factors influencing developmental deficits in IUGR populations.

    Main Methods:

    • Prospective follow-up study involving 76 IUGR children and 88 controls, assessed from 1 to 6 years of age.
    • Developmental assessments included motor, cognitive, and language milestones.
    • Socioeconomic status was measured using the Blishen score at birth.

    Main Results:

    • IUGR children remained smaller than controls between 12 and 60 months.
    • No significant differences were found in motor, cognitive, or language developmental delays, or in vision and hearing tests.
    • Performance in senior kindergarten was comparable between groups.
    • A significant association was observed between socioeconomic status and the occurrence of motor and cognitive deficits.

    Conclusions:

    • Children with IUGR, mature at birth, exhibit comparable developmental trajectories to peers without IUGR by school age.
    • Early childhood growth and socioeconomic factors play a role in developmental outcomes.
    • Further research into socioeconomic influences on IUGR child development is warranted.

    More Related Videos

    A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis06:19

    A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

    Published on: January 7, 2018

    Transuterine Fetal Tracheal Occlusion Model in Mice06:31

    Transuterine Fetal Tracheal Occlusion Model in Mice

    Published on: February 5, 2021

    Related Concept Videos

    Regression Toward the Mean01:52

    Regression Toward the Mean

    Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
    Teratogenicity01:07

    Teratogenicity

    The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
    Intrauterine Drug Delivery Systems01:21

    Intrauterine Drug Delivery Systems

    Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...