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Chronic urticaria dnd vasculitis

P Small, D Barrett, E Champlin

    Annals of Allergy
    |March 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Chronic urticaria can present with arthritis. Diagnostic tests for this condition, including complement (CH50) and immune complexes (IC), were not consistently abnormal in affected patients.

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    Area of Science:

    • Immunology
    • Rheumatology
    • Dermatology

    Background:

    • Chronic urticaria is a common condition.
    • Arthritis can be a rare manifestation of chronic urticaria.

    Purpose of the Study:

    • To investigate the clinical characteristics and diagnostic findings of chronic urticaria patients presenting with arthritis.

    Main Methods:

    • Review of 231 chronic urticaria patients.
    • Analysis of clinical presentation, sedimentation rates, complement (CH50) levels, serum immune complexes (IC), and skin biopsies.

    Main Results:

    • Eight out of 231 patients had concurrent arthritis.
    • Elevated sedimentation rates were observed in all eight patients.
    • Depressed complement (CH50) in five patients and elevated immune complexes (IC) in two.

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  • Skin biopsies were abnormal in only four patients and did not correlate with CH50 or IC levels.
  • No single diagnostic test was consistently abnormal across all patients.

    • Conclusions:

    • Arthritis is an uncommon presentation of chronic urticaria.
    • A combination of clinical evaluation and laboratory tests may be needed for diagnosis.
    • Further research is needed to understand the underlying mechanisms.