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Thyroid function screening in new psychiatric admissions

J E Morley, R B Shafer

    Archives of Internal Medicine
    |March 1, 1982
    PubMed
    Summary
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    Thyroid function screening is valuable in psychiatric patients. Many patients showed temporary thyroid abnormalities during short-term admissions, particularly those with schizophrenia or amphetamine abuse.

    Area of Science:

    • Psychiatry
    • Endocrinology
    • Clinical Medicine

    Background:

    • Thyroid function screening may offer significant value in managing psychiatric patients.
    • Understanding the prevalence and nature of thyroid abnormalities in this population is crucial for effective treatment.
    • Short-term psychiatric admissions present a unique context for evaluating thyroid function.

    Purpose of the Study:

    • To determine the incidence of thyroid abnormalities in psychiatric patients during short-term hospitalizations.
    • To identify specific psychiatric diagnoses or substance abuse issues associated with higher rates of thyroid dysfunction.

    Main Methods:

    • Conducted thyroid function tests on 386 psychiatric patients during short-term admissions.
    • Measured free thyroxine index (FT4I) and free triiodothyronine index (FT3I).

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  • Performed retesting two to three weeks after hospitalization for a subset of patients.

    • Main Results:

    • Elevated FT4I and FT3I were observed in 19% of the psychiatric patient cohort.
    • Higher incidences of elevated thyroid function tests were noted in paranoid schizophrenics (38%) and patients with amphetamine abuse (32%).
    • Thyroid function normalized in most patients upon retesting, suggesting transient abnormalities.

    Conclusions:

    • Transient thyroid function abnormalities are common in psychiatric patients during short-term admissions.
    • Specific conditions like paranoid schizophrenia and amphetamine abuse are linked to increased thyroid dysfunction.
    • Further research on serial thyroid function testing is needed to establish optimal timing post-admission.