Lung carcinogenesis by procarbazine chlorate in BALB/c mice

A study of the carcinogenic action of procarbazine chlorate in BALB/c/Cb/Se mice showed that this substance significantly increases the incidence or lung tumours in both sexes. The induced tumors were alveolar-lining, papillary and alveolar-papillary type carcinomas with a tendency to invade the bronchial wall.