The effect of age on the pharmacokinetics of oxprenolol

The pharmacokinetics of oxprenolol have been studied in young and healthy elderly volunteers. Drug concentrations in plasma and urine have been measured after a single 80-mg dose of oxprenolol and again after repeated administration (80 mg twice daily) for a period of 1 week. It has been shown that multiple dosing does not result in oxprenolol accumulation in either group and that age has no effect on the pharmacokinetics of this drug.