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Influence of age on atrioventricular conduction intervals in children with and without atrial septal defect

D J Shiku, M Stijns, J P Lintermans

    Journal of Electrocardiology
    |January 1, 1982
    PubMed

    Insights

    Secundum atrial septal defects (ASD) prolong atrioventricular conduction intervals, particularly in older children. This age-related impact on conduction involves both the PA and HV intervals.

    Area of Science:

    • Cardiology
    • Pediatric Electrophysiology

    Background:

    • Secundum atrial septal defects (ASD) are common congenital heart abnormalities.
    • Atrioventricular (AV) conduction properties in pediatric ASD patients are not fully understood.

    Purpose of the Study:

    • To investigate the impact of secundum ASD on His bundle electrogram intervals.
    • To determine if this impact is age-dependent.

    Main Methods:

    • His bundle electrograms were recorded in 42 pediatric patients with ASD and 50 age-matched controls.
    • Electrophysiological intervals including PA, AH, HV, and PR were analyzed.
    • Data was stratified by age groups to assess age-related changes.

    Main Results:

    • ASD patients exhibited significantly prolonged PA and PR intervals compared to controls.
    • Age-related increases in AH, HV, and PR intervals were observed in older ASD children.
    • Significant differences in PA, HV, and PR intervals emerged between ASD patients and controls in older age groups (4-8 and 9-16 years).

    Conclusions:

    • Secundum ASD significantly impacts AV conduction in a manner that is age-dependent.
    • The effects on AV conduction involve both early (PA) and distal (HV) His-bundle intervals.
    • Early detection and management of AV conduction abnormalities in pediatric ASD are crucial.

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