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Radical prostatectomy for stage B2 prostatic cancer

R G Middleton, J A Smith

    The Journal of Urology
    |April 1, 1982
    PubMed
    Summary

    Pelvic lymphadenectomy helps identify patients with stage B2 prostate cancer suitable for radical prostatectomy. This staging procedure prevents unnecessary surgeries by confirming tumor confinement to the prostate gland.

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    Area of Science:

    • Urology
    • Oncology

    Background:

    • Stage B2 prostate cancer presents diagnostic challenges for radical prostatectomy.
    • Rectal examination inaccuracies and potential extracapsular extension complicate treatment decisions.

    Purpose of the Study:

    • To evaluate the utility of pelvic lymphadenectomy in staging clinical stage B2 prostate carcinoma.
    • To identify appropriate candidates for radical prostatectomy in this patient group.

    Main Methods:

    • A 10.5-year study involving 87 patients with clinical stage B2 prostate cancer.
    • Staging pelvic lymphadenectomy was performed, followed by radical prostatectomy in node-negative patients.

    Main Results:

    • 28% of patients had positive pelvic lymph nodes and were excluded from prostatectomy.
    • Of 50 node-negative patients undergoing prostatectomy, 86% had tumors confined to the prostate histologically.

    Conclusions:

    • Pelvic lymphadenectomy is crucial for selecting stage B2 prostate cancer patients for radical prostatectomy.
    • This approach ensures that surgery is reserved for cases with a high likelihood of localized disease.

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