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Urinary tract infections (UTIs) in infants show higher rates in males under three months and uncircumcised infants. Sepsis and urinary abnormalities are common, but all infants responded well to treatment.
Area of Science:
- Pediatrics
- Infectious Diseases
- Urology
Background:
- Urinary tract infections (UTIs) are common in infants.
- Understanding demographic and clinical features is crucial for early diagnosis and management.
- Infant UTIs can lead to serious complications like sepsis and renal damage.
Purpose of the Study:
- To present the clinical and laboratory features of UTIs in 100 infants.
- To analyze age- and sex-specific UTI prevalence.
- To identify associated complications and treatment outcomes.
Main Methods:
- Retrospective analysis of 100 infants aged 5 days to 8 months with confirmed UTIs.
- Data collection on patient demographics, clinical presentation, laboratory findings, and imaging results.
- Evaluation of treatment response to antimicrobial therapy.
Main Results:
- Male predominance (75%) in infants <3 months old; female predominance in older infants (89%).
- 95% of infected infants were uncircumcised.
- Sepsis occurred in 31% of neonates, decreasing with age.
- Urinary system abnormalities found in 45% of females vs. 7% of males.
- All infants showed prompt response to antimicrobial treatment.
Conclusions:
- UTI presentation in infants varies significantly by age and sex.
- Uncircumcised status and early male gender are risk factors for infant UTIs.
- Prompt antimicrobial therapy is effective, but vigilance for sepsis and urinary abnormalities is essential.
Abstract:
The clinical and laboratory features of urinary tract infections in 100 infants aged 5 days to 8 months are presented. Of the patients in the first three months of life 75% were boys, and of infants aged 3 to 8 months only 11% were boys; 95% of the infants were uncircumcised. Sepsis was documented in 31% of neonates, 21% of infants aged 1 to 2 months, 14% of those aged 2 to 3 months, and 5.5% of infants greater than 3 months of age. Roentgenographic abnormalities of the urinary system were found in 45% of female and 7% of male infants. All infants responded promptly to antimicrobial therapy. The possible factors related to the predominance of male infants with urinary tract infections in the first three months of life are discussed.