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[Changes in blood composition and properties in children with external fistulae]

M G Arbuliev, G A Gadzhimirzaev, A D Magomedov

    Vestnik Khirurgii Imeni I. I. Grekova
    |February 1, 1982
    PubMed

    Insights

    Small intestine fistulas in children cause blood volume loss and clotting issues. Treatment with blood flow-improving drugs and anticoagulants showed positive outcomes in both pediatric patients and dogs.

    Area of Science:

    • Pediatric Surgery
    • Hematology
    • Gastroenterology

    Context:

    • Small intestine fistulas present a significant clinical challenge.
    • Understanding the hematological impact is crucial for patient management.

    Purpose:

    • To investigate the blood composition and properties in children with small intestine fistulas.
    • To compare findings with experimental canine models.
    • To evaluate the efficacy of specific therapeutic interventions.

    Summary:

    • Children with small intestine fistulas exhibited hypovolemia, electrolyte imbalances, increased hematocrit and viscosity.
    • Coagulogram and thromboelastogram tests indicated disseminated intravascular coagulation.
    • Similar hematological changes were observed in dogs with duodenal fistulas.

    Impact:

    • Findings highlight critical hematological derangements associated with small intestine fistulas.
    • Therapeutic strategies involving rheological agents and anticoagulants demonstrate improved treatment outcomes.
    • This research provides insights for managing complex surgical cases and their systemic effects.

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