Related Experiment Video
Updated: Aug 14, 2026

Testing the Efficacy of Pharmacological Agents in a Pericardial Target Delivery Model in the Swine
Published on: July 7, 2016
Abstract:
Extracardiac sounds secondary to cardiac pacing are well known, but the murmurs originating in the heart after pacemaker insertion are rare. A patient who developed musical systolic murmur following temporary transvenous endocardial pacemaker insertion is described. It is concluded that the murmur was produced by vibrations caused by the pacing catheter and the tricuspid valve or some other intracardiac structure.
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Auscultation is the process of listening to these internal body sounds using a stethoscope. The heart produces four types of sounds, but only two—S1 and S2—can usually be heard with a stethoscope.
S1, also known as the "lub" sound, is caused by the closure of atrioventricular (A-V) valves at the...
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