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Related Experiment Videos

Retropulsion-propulsion in equine large colon

A F Sellers, J E Lowe, C J Drost

    American Journal of Veterinary Research
    |March 1, 1982
    PubMed
    Summary

    Equine large colon motility is regulated by electrical coupling in the pelvic flexure, influencing digestion. Disrupting blood flow or using certain acaricides can lead to colic and digestive issues in horses.

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    Area of Science:

    • Veterinary Science
    • Equine Physiology
    • Gastrointestinal Motility

    Background:

    • The equine large colon exhibits complex myoelectrical activity essential for digestion.
    • Electrical coupling between circular and longitudinal muscle coats facilitates coordinated motility.
    • The pelvic flexure acts as a pacemaker for myoelectrical events, regulating digesta flow and fermentation.

    Purpose of the Study:

    • To investigate the role of electrical coupling in equine large colon motility.
    • To determine the effects of impaired blood flow and acaricide administration on colon function.
    • To understand the mechanisms underlying colic and large colon obstruction.

    Main Methods:

    • Direct electrical coupling assessment of equine "midcolon" muscle coats.

    Related Experiment Videos

  • Experimental induction of parasitic cranial mesenteric arteritis using Strongylus vulgaris larvae in foals.
  • Administration of an acaricide associated with colic in adult horses.
  • Monitoring intraluminal pressure events and myoelectrical action potentials.

    • Main Results:

    • Direct electrical coupling was confirmed between circular and longitudinal muscle coats.
    • Cooling intestinal contents slowed myoelectrical events without adverse effects.
    • Parasitic arteritis in foals led to abdominal pain in some, with no gross lesions.
    • Acaricide administration induced dissociation of colon divisions, correlating with colic and obstruction.

    Conclusions:

    • The pelvic flexure's pacemaker function is crucial for normal equine large colon motility.
    • Disruption of blood flow or specific acaricide use can impair colon function, leading to colic.
    • Myoelectrical dissociation is a key factor in colic pathogenesis and large colon obstruction.