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Mucormycosis of the temporal bone
The Annals of Otology, Rhinology, and Laryngology
|January 1, 1982
Summary
This case study details mucormycosis, a fungal infection, spreading from the nasopharynx to the temporal bone in a diabetic patient. It highlights cranial nerve palsies and hearing loss due to extensive tissue damage and vascular involvement.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Pathology
Background:
- Mucormycosis is a rare but aggressive fungal infection.
- Uncontrolled diabetes mellitus is a significant risk factor for mucormycosis.
Observation:
- A 60-year-old female with uncontrolled diabetes presented with cranial nerve palsies and hearing loss.
- Infection spread from the nasopharynx to the temporal bone via the eustachian tube and tensor tympani muscle.
- The internal carotid artery was involved with mycotic thrombosis and rupture.
Findings:
- The infection spread along nerve pathways and via mycotic emboli to the labyrinth and middle ear.
- Temporal bone pathology included granulomatous inflammation, necrosis, and ischemic infarction.
- The infection invaded the vestibule through the oval window.
Implications:
- This case underscores the aggressive nature of mucormycosis in immunocompromised individuals.
- Early diagnosis and aggressive management are crucial for favorable outcomes.
- Understanding the pathways of spread is vital for effective treatment strategies.