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Viral studies in benign acute childhood myositis
Archives of Neurology
|May 1, 1982
Abstract:
Thirty-five cases of benign acute childhood myositis followed infections with influenza A or B. Two children had recurrent myositis associated with infections of different influenza types. None of the children had acute-phase antibody titers to the infecting type of influenza. These results are consistent with the proposal that benign acute childhood myositis can occur only with the initial infection of a viral type.
Insights
Benign acute childhood myositis often follows influenza A or B infections. Recurrence is rare and suggests initial infection with a specific viral type is necessary for this condition.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Background:
- Benign acute childhood myositis (BACM) is a transient condition.
- It is frequently associated with influenza virus infections.
Purpose of the Study:
- To investigate the relationship between initial influenza infection and the occurrence of BACM.
- To explore the possibility of BACM recurrence with different influenza types.
Main Methods:
- Retrospective analysis of 35 children diagnosed with BACM.
- Review of infection history, specifically influenza A and B.
- Assessment of acute-phase antibody titers to infecting influenza types.
Main Results:
- Thirty-five cases of BACM were identified following influenza A or B infection.
- Two children experienced recurrent myositis with different influenza types.
- No children with BACM had detectable acute-phase antibody titers to the specific infecting influenza type.
Conclusions:
- BACM may primarily occur during the initial infection with a specific influenza viral type.
- The findings support the hypothesis that prior immunity to a viral type may prevent subsequent BACM episodes.