The influence of vitreous change on vitreous fluorophotometry

Thirteen patients with retinitis pigmentosa were graded in terms of vitreous change and compared by vitreous fluorophotometry to an equal number of normal patients. A highly significant difference was found between groups. A high correlation was also noted between severity of vitreous change and midvitreous fluorophotometry values. Certain types of vitreous detachments appear to produce a characteristic "cancer hump" in the resultant data. A possible explanation for the increased values is discussed.