Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ophthalmic fluorophotometry: a new solid state fluorophotometer

D P Jones, W R Webber, A T Smith

    Journal of Biomedical Engineering
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparing coronary artery cross-sectional area among asymptomatic South Asian, White, and Black participants: the MASALA and CARDIA studies.

    BMC cardiovascular disorders·2024
    Same author

    Malignant transformation in a cohort of patients with oral epithelial dysplasia.

    The British journal of oral & maxillofacial surgery·2021
    Same author

    Three changes to reduce the loss of dual degree trainees from OMFS national specialty selection in the UK: evidence based proposals.

    The British journal of oral & maxillofacial surgery·2021
    Same author

    Connectivity of the Cingulate Sulcus Visual Area (CSv) in Macaque Monkeys.

    Cerebral cortex (New York, N.Y. : 1991)·2020
    Same author

    Hyperexcitability of brain stem pathways in cerebral palsy.

    Journal of neurophysiology·2018
    Same author

    Measuring health-related benefit and quality of care in oral and maxillofacial surgery: British Association of Oral and Maxillofacial Surgeons Outcomes Project.

    The British journal of oral & maxillofacial surgery·2018
    Same journal

    Comparative study of the function of the Abiomed polyurethane heart valve for use in left ventricular assist devices.

    Journal of biomedical engineering·1993
    Same journal

    AZTDIS--a two-phase real-time ECG data compressor.

    Journal of biomedical engineering·1993
    Same journal

    Validation of an automated method of three-dimensional finite element modelling of bone.

    Journal of biomedical engineering·1993
    Same journal

    Three dimensional shape reconstruction and finite element analysis of femur before and after the cementless type of total hip replacement.

    Journal of biomedical engineering·1993
    Same journal

    The Rancho EMG analyzer: a computerized system for gait analysis.

    Journal of biomedical engineering·1993
    Same journal

    Preparation and in vivo evaluation of a newly developed bioglass ceramic.

    Journal of biomedical engineering·1993
    See all related articles

    A novel low-voltage ophthalmic fluorophotometer offers stable and affordable eye measurements. This instrument accurately quantifies sodium fluorescein concentrations, enabling precise tear flow and corneal permeability assessments.

    Area of Science:

    • Ophthalmology
    • Biomedical Instrumentation

    Background:

    • Accurate measurement of ocular fluid dynamics is crucial for diagnosing and monitoring various eye conditions.
    • Existing fluorophotometry instruments can be expensive and complex.

    Purpose of the Study:

    • To describe a new, stable, and cost-effective low-voltage ophthalmic fluorophotometer.
    • To validate the instrument's capability for measuring sodium fluorescein concentration in ocular tissues.

    Main Methods:

    • Development of a low-voltage instrument integrating a solid-state photodetector.
    • Incorporation of a high-gain, low-noise amplification and synchronous detection system.
    • Utilized sodium fluorescein as a tracer for concentration measurements.

    Main Results:

    Related Experiment Videos

    • The instrument achieves stable measurements down to 100 ng/ml (0.26 mumol/l) sodium fluorescein concentration.
    • Demonstrated reliable estimation of corneal permeability.
    • Preliminary data on tear turnover rate measurements were obtained.

    Conclusions:

    • The developed fluorophotometer is a stable, inexpensive, and reliable tool for ophthalmic research.
    • It enables accurate assessment of corneal permeability and tear flow rates.
    • The instrument shows promise for clinical applications in evaluating ocular surface disease and tear dynamics.