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Updated: Aug 18, 2026

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film
Published on: July 10, 2016
[Structure and physico-chemical properties of artificial lipid-proteolipid membranes]
Abstract:
Stable flat lipid-proteolipid membranes were obtained from lipid-proteolipid mixture of cattle brain white matter. Equilibrium values of resistance, surface tension and optical thickness of these membranes in KCl and NaCl solutions were measured in the temperature range 25--50 degrees C. An artificial lipid-proteolipid membrane was shown to comprise a mosaic of bilayer lipid regions and proteolipid nodes occupying about 30% of the surface area and adjacent to the aqueous medium. In relation to ionic strength and temperature of the aqeous medium the resistance of such membranes may vary within 10(5)--10(8) Ohm cm2, whereas tension and optical thickness vary comparatively little. There exist two stationary levels of membrane conductivity, and reversible spontaneous transitions between them at fixed temperature and ionic strength of the aqueous medium may proceed.
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