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Related Experiment Videos

Vagotogenic cholecystitis

C J Schein, M I Gliedman

    The American Journal of Gastroenterology
    |June 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Truncal vagotomy can cause acute cholecystitis in dogs with gallstones. This complication was also seen in three patients, suggesting prophylactic gallbladder surgery alongside vagotomy when gallstones are present.

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    Area of Science:

    • Gastroenterology
    • Surgical Pathology

    Background:

    • Truncal vagotomy is a surgical procedure to reduce stomach acid.
    • Gallstones (cholelithiasis) are a common condition.
    • The interaction between vagotomy and cholelithiasis is not well-understood.

    Observation:

    • Truncal vagotomy was observed to induce acute cholecystitis in dogs with gallstones.
    • A similar clinical sequence was incidentally observed in three human patients.

    Findings:

    • The study establishes a link between truncal vagotomy and acute cholecystitis in the presence of gallstones.
    • This complication appears to be reproducible in an animal model.

    Implications:

    • Patients undergoing truncal vagotomy with known cholelithiasis may require concurrent gallbladder intervention.
  • Consider prophylactic cholecystectomy or other procedures to prevent post-vagotomy cholecystitis.