Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Human pattern-evoked retinal responses are altered by optic atrophy

W W Dawson, T M Maida, M L Rubin

    Investigative Ophthalmology & Visual Science
    |June 1, 1982
    PubMed
    Summary

    Electrical signals from the optic nerve and ganglion cells are crucial for pattern-evoked retinal responses (PERR). Damage to the optic nerve selectively eliminates PERR, not electroretinogram responses.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Martin's Bandage.

    The Southern medical record·2022
    Same author

    The President's Address.

    The Dental register·2021
    Same author

    Synthesis and turnover of lipid and protein components of frog retinal rod outer segments.

    Neurochemistry international·2010
    Same author

    Time-specific intraocular pressure curves in Rhesus macaques (Macaca mulatta) with laser-induced ocular hypertension.

    Veterinary ophthalmology·2004
    Same author

    Corneal thickness and endothelial cell density measured by non-contact specular microscopy and pachymetry in Rhesus macaques (Macaca mulatta) with laser-induced ocular hypertension.

    Experimental eye research·2003
    Same author

    [Retinal hazard from blue light emitting diode].

    Nippon Ganka Gakkai zasshi·2001

    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Visual Electrophysiology

    Background:

    • Assessing the functional integrity of the visual pathway is critical in diagnosing optic nerve damage.
    • The electroretinogram (ERG) and pattern-evoked electroretinogram (PERG) are electrophysiological tests used to evaluate retinal and optic nerve function, respectively.

    Observation:

    • Electrical signals were recorded from the eyes and scalp of a patient with unilateral traumatic optic nerve section.
    • The affected eye had no light perception, a Marcus Gunn pupil, and an atrophic optic disc.
    • The electroretinogram (ERG) responses on the lesioned side were normal.

    Findings:

    • No pattern-evoked retinal response (PERR) was detected on the lesioned side.
    • No recordable visual-evoked response (VER) was present.
    • The study suggests that the optic nerve and ganglion cells are selectively responsible for the PERR potential.

    Implications:

    • This finding highlights the specific role of the optic nerve and ganglion cells in generating PERR.
    • It underscores the utility of PERR in differentiating optic nerve dysfunction from retinal dysfunction.
    • Understanding these distinctions aids in the diagnosis and management of visual pathway disorders.

    Related Experiment Videos