Calcifying panniculitis associated with renal failure. A case of Selye's calciphylaxis in man

Nephrotic syndrome developed in a 45-year-old white woman who had insulin-dependent diabetes mellitus. Following diuretic therapy and intravenous infusions of albumin, painful induration developed in the thighs and abdomen. A biopsy of the affected subcutaneous tissue demonstrated interstitial deposition of calcium. In this case of calcifying panniculitis, the conditions for calciphylaxis appear to have been present.