[Plasma prostaglandins in hypo-and hypertensive neurocirculatory dystonia]

Investigations were carried out at rest and after physical exercise (50 and 75% from maximum) with pressor Fl-alpha and F2 alpha and depressor (A, E) fraction of prostaglandins (PG) in 10 healthy individuals, in 10 patients with neurocirculatory dystoniaa with hypertension and in 10 patients with neurocirculatory dystonia with hypotension. In patients with hypertension at rest as compared to the healthy individuals there was increase of content of pressor and decrease of depressor fractions of PG, in patients with hypotension changes in PG were of the reverse type. In adaptation to physical load at different stage of load levels definite trends in changes in the PG content have been recorded, close to such changes in the healthy subjects and patients with hypotension, and a reverse trend in persons with hypertension.