Related Experiment Videos
[Treatment of gonarthrosis]
Medizinische Klinik (Praxis-Ausg.)
|February 12, 1982
Summary
Superoxide dismutase (Orgotein) effectively treated gonarthrosis and related joint conditions in 91% of patients. This antiphlogistic compound provided long-lasting pain relief with good tolerance in most cases.
Area of Science:
- Biochemistry
- Pharmacology
Context:
- Investigated the efficacy of superoxide dismutase (Orgotein) in managing joint conditions.
- Focused on out-patients with gonarthrosis, post-operative/post-traumatic irritation, and chondropathy.
Purpose:
- To evaluate the therapeutic effect of intra-articular Orgotein injections.
- To assess the efficacy, relapse rate, and tolerance of Orgotein in treating joint ailments.
Summary:
- Orgotein (4 mg) was administered intra-articularly weekly to 89 out-patients.
- 81 out of 89 patients (91%) showed treatment efficacy, with 75 achieving long-lasting pain relief.
- Good tolerance was reported, though three patients experienced reversible injection-site reactions.
Impact:
- Orgotein demonstrated significant potential as an antiphlogistic agent for joint disorders.
- The study highlights the long-term pain relief and favorable outcomes achievable with Orgotein therapy.
- Identified potential for localized, reversible adverse effects with repeated administration.