Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Naloxone and clinical anesthesia]

E Romano, A Gullo, P Simoniti

    Minerva Anestesiologica
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Naloxone is an effective narcotic antagonist for reversing postoperative respiratory depression caused by anesthesia or morphine. Careful dosage titration and patient monitoring are crucial due to potential side effects.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Evidence for the Collective Nature of Radial Flow in Pb+Pb Collisions with the ATLAS Detector.

    Physical review letters·2026
    Same author

    Evidence for the Dimuon Decay of the Higgs Boson in pp Collisions with the ATLAS Detector.

    Physical review letters·2025
    Same author

    Secondary angle-closure by pupillary block in a pseudophakic vitrectomized patient.

    Journal francais d'ophtalmologie·2025
    Same author

    ESMO guidance on the use of Large Language Models in Clinical Practice (ELCAP).

    Annals of oncology : official journal of the European Society for Medical Oncology·2025
    Same author

    Evidence for Longitudinally Polarized W Bosons in the Electroweak Production of Same-Sign W Boson Pairs in Association with Two Jets in pp Collisions at sqrt[s]=13  TeV with the ATLAS Detector.

    Physical review letters·2025
    Same author

    Observation of tt[over ¯] Production in Pb+Pb Collisions at sqrt[s_{NN}]=5.02  TeV with the ATLAS Detector.

    Physical review letters·2025

    Area of Science:

    • Anesthesiology
    • Pharmacology

    Context:

    • Postoperative respiratory depression is a significant concern following anesthesia and opioid administration.
    • Naloxone, a narcotic antagonist, is indicated for managing opioid-induced respiratory depression.

    Purpose:

    • To outline the appropriate use of naloxone in managing postoperative respiratory depression.
    • To provide guidelines for naloxone administration and patient monitoring.

    Summary:

    • Naloxone effectively reverses respiratory depression from morphine, LAN, and narcotic anesthesia.
    • Individualized dosing is essential, starting with 0.1 mg IV increments until spontaneous breathing returns.
    • Post-administration, a 50% intramuscular dose after 30 minutes and 4-6 hours of observation are recommended.
    • Potential drawbacks include heart rate disturbances and hypertension crises, necessitating careful patient management.

    Related Experiment Videos

    Impact:

    • Provides evidence-based guidelines for safe and effective naloxone use in clinical practice.
    • Aims to improve patient outcomes by mitigating risks associated with opioid-induced respiratory depression.
    • Highlights the importance of individualized treatment and vigilant monitoring in postoperative care.