Uterine stromatosis: a report of 33 cases

Uterine stromatosis is an uncommon intramyometrial lesion. The present study reviews the clinicopathologic aspects of 33 cases, 9 of which were treated at The Johns Hopkins Hospital, whereas 24 were referred to the gynecologic pathology laboratory. In the series it was noted that progesterone therapy was able to control the spread of the condition and to cause regression of extrauterine disease for periods up to 9 years. Criteria for the diagnosis of malignancy in stromatosis are discussed.