Clinico-chemical changes in goats given carbon tetrachloride
Related Experiment Video
Updated: Oct 23, 2026

How to Create Conditioned Taste Aversion for Grazing Ground Covers in Woody Crops with Small Ruminants
Published on: April 30, 2016
Abstract:
Six healthy castrated male goats were each given 1.0, 1.25 or 1.5 ml of carbon tetrachloride per 10 kg BW by stomach tube (2 animals at each dose level). Definite signs of dose dependant liver damage were seen, starting about 4 hours after administration of the drug. The clinico-chemical changes included increased total and conjugated plasma bilirubin, decreased blood clotting activity, and increased activities of P-ASAT and P-GT. Further experiments are needed in animals afflicted with liverflukes to establish the lowest possible anthelmintic dose of carbon tetrachloride.
Related Concept Videos
Anticholinesterase Agents: Poisoning and Treatment
Irreversible agents form a strong bond with the cholinesterase enzyme, making it inactive. The breakdown of the phosphorylated enzyme is slower than the...
Phase I Reactions: Oxidation of Aliphatic and Aromatic Carbon-Containing Systems
Oxidation reactions are fundamental in aromatic carbon-containing systems. An example is the hydroxylation of phenobarbital, a process that transforms it into...
Toxicity Testing in Animals
Toxidromes: Clinical Features

