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Related Experiment Videos

[Occult papillary thyroid cancer]

A M Schindler

    Schweizerische Medizinische Wochenschrift
    |March 6, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Occult sclerosing carcinoma of the thyroid, a rare thyroid cancer, was found in 7.7% of surgical thyroidectomies. Most patients recovered well after conservative treatment, with a low recurrence rate.

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    Area of Science:

    • Endocrinology
    • Oncology
    • Pathology

    Context:

    • Review of surgically removed thyroids over ten years in Geneva.
    • Analysis of 133 consecutive autopsies for thyroid gland abnormalities.

    Purpose:

    • To present the clinical and morphological aspects of occult sclerosing carcinoma of the thyroid.
    • To determine the incidence and characteristics of this rare thyroid malignancy.

    Summary:

    • Occult sclerosing carcinoma represented 7.7% of malignant thyroid tumors and 20% of papillary carcinomas in surgical cases.
    • Mean age of diagnosis was 46.6 years, predominantly in women, often presenting as nodular goiters.
    • Conservative treatment with subtotal thyroidectomy and TSH suppression led to a 91% disease-free rate over 4-13 years.
    • Autopsy findings revealed occult tumors in 2.3% of cases, including microcarcinomas.

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    Impact:

    • Highlights the prevalence of occult sclerosing carcinoma in surgical and autopsy thyroid specimens.
    • Provides insights into clinical presentation, treatment outcomes, and recurrence patterns.
    • Compares incidence rates with international studies, noting significant geographical variations.