Solitary intracranial plasmacytoma

Area of Science:

• Neurology
• Oncology
• Pathology

Background:

• Solitary plasmacytomas are rare plasma cell neoplasms.
• Intracranial involvement is exceptionally uncommon, posing diagnostic and therapeutic challenges.

Observation:

• A case report details a solitary plasmacytoma affecting the left cerebral convexity, dura mater, falx, and sagittal sinus.
• The patient underwent subtotal tumor excision followed by radiation therapy.

Findings:

• The patient remained disease-free seven years post-diagnosis, indicating a favorable long-term outcome.
• Electrophoretic studies of cerebrospinal fluid and serum proteins are crucial for diagnosis and monitoring.

Implications:

• This case underscores the potential for successful management of rare intracranial plasmacytomas.
• Highlights the diagnostic utility of protein electrophoresis in plasma cell disorders affecting the central nervous system.