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[The cardiovascular risk profile of the long-term diabetic]
Insights
Long-term diabetics face significant cardiovascular risks from hypertension, high triglycerides, high cholesterol, and high uric acid. Early recognition and management of these risk factors are crucial for preventing macroangiopathy in diabetic patients.
Area of Science:
- Cardiology
- Endocrinology
- Metabolic Syndrome
Context:
- Long-term diabetes mellitus significantly increases the risk of macroangiopathy.
- Cardiovascular risk factors including overweight, hypertension, hypertriglyceridemia, hypercholesterolemia, and hyperuricemia are prevalent in diabetics.
- Understanding the cardiovascular risk profile in long-term diabetics is essential for preventive strategies.
Purpose:
- To analyze the cardiovascular risk profile of long-term diabetic patients.
- To compare the prevalence of cardiovascular risk factors in long-term diabetics versus the general population.
- To investigate the association of cardiovascular risk factors with disease duration and age in diabetics.
Summary:
- Analysis of 217 long-term diabetics (average disease duration 19.8 years, average age 60.2 years) revealed higher frequencies of hypertension, hypertriglyceridemia, hypercholesterolemia, and hyperuricemia compared to normal individuals.
- While weight did not differ significantly, serum uric acid levels increased with age and were higher in long-term diabetics than in newly diagnosed ones.
- The association of these five risk factors was less pronounced in long-term diabetics compared to newly diagnosed diabetics, considering similar age structures.
Impact:
- Highlights the increased cardiovascular risk in long-term diabetics, emphasizing the need for proactive management of hypertension, dyslipidemia, and hyperuricemia.
- Suggests that early identification and intervention for cardiovascular risk factors in newly diagnosed diabetes (Type I and II) and impaired glucose tolerance can improve long-term outcomes.
- Underscores the importance of preventive medicine in mitigating macroangiopathy complications in diabetic populations.
Abstract:
The long-term diabetic is in a considerable degree endangered by macroangiopathy. With a high probability their profile is influenced by the factors of cardiovascular endangering overweight (Broca-weight greater than or equal to 110%), hypertension (RR greater than or equal to 160/95 mm Hg), hypertriglyceridaemia (greater than or equal to 200 mg/dl), hypercholesterolaemia (greater than or equal to 260 mg/dl) and hyperuricaemia (greater than or equal to 6.5 mg/dl in male and greater than or equal to 6.0 mg/dl in female). Our analysis of the profile of the cardiovascular risk of 217 long-term diabetics with an average duration of the disease of 19.8 years and an average age of 60.2 years showed in comparison to normal persons an increased frequency of hypertension, hypertriglyceridaemia, hypercholesterolaemia and hyperuricaemia, whereas the weight did not differ from a normal population. Taking into consideration the same age structure the association of the examined 5 signs of risk is less narrow in the long-term diabetic than in the newly detected diabetic. With growing age the values of uric acid of the serum increase; in long-term diabetics their concentration surpasses that one of newly detected diabetic patients. From the point of view of preventive medicine factors of cardiovascular risk must be recognized already in the newly detected diabetes of type I or II as well as in disturbed glucose tolerance and, as far as possible, be influenced in the sense of an improvement of the profile of the risk.