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[Liver cirrhosis in autopsy material within 48 years. I. Changes of prevalence, regional differences (author's
Abstract:
Comparative studies on a total of 41628 autopsies from the Institutes of Pathology of Wuppertal and Tuebingen revealed a 2,97 fold increase of liver cirrhosis in Wuppertal and 2,29 fold rise of prevalence in Tuebingen between 1946 and 1975. In Tuebingen this increasing prevalence preponderates in men, in Wuppertal in women. Thus, between 1964-1975 in Tuebingen the prevalence of liver cirrhosis in men exceeds liver cirrhosis in women 2,1 fold, in Wuppertal 1,1 fold only. After World War II a considerable increase was observed in both Institutes within 25 years, which reached a maximum with 8,2% of all adults in Tuebingen in 1969 and 11,8% in 1972 in Wuppertal, especially owing to an increase of portal cirrhosis. Since then no further rise has been noticed.