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Regional hyperthermia for cancer

H W Baker, P A Snedecor, J C Goss

    American Journal of Surgery
    |May 1, 1982
    PubMed
    Summary

    Regional hyperthermia combined with cancer therapies improved patient outcomes. This innovative treatment demonstrated significant tumor response rates and notable pain relief in advanced cancer patients.

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    Pathology·2001

    Area of Science:

    • Oncology
    • Medical Physics

    Background:

    • Advanced cancer presents significant treatment challenges.
    • Combining therapies is crucial for improving patient outcomes.

    Purpose of the Study:

    • To evaluate the clinical efficacy of regional hyperthermia.
    • To assess its combination with radiation therapy and/or chemotherapy in advanced cancer patients.

    Main Methods:

    • 107 patients with advanced cancer received regional hyperthermia.
    • Hyperthermia was combined with radiation therapy, chemotherapy, or both.
    • Radiofrequency equipment was used for tumor heating.
    • Eight patients underwent subsequent surgery.

    Main Results:

    • Complete response rates were 16%, with partial response rates at 52%.
    • Significant pain relief was observed across responders and non-responders.
    • The radiofrequency equipment demonstrated efficacy with minimal adverse effects.

    Conclusions:

    • Regional hyperthermia is a viable and effective addition to standard cancer treatments.
    • The combination therapy shows promise in managing advanced cancer and alleviating pain.

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