Related Experiment Video
Updated: Aug 14, 2026

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector - the Trinity Clip - in a Porcine Off-pump Bypass Model
Published on: November 24, 2014
Single aortic cross-clamping for distal and proximal anastomoses in coronary surgery: an alternative to conventional
Insights
This study introduces a single cross-clamping technique during coronary artery bypass surgery using hypothermic cardiopulmonary bypass. This method enhances surgical precision and patient safety by minimizing aortic manipulation, ensuring complete heart revascularization.
Area of Science:
- Cardiovascular Surgery
- Cardiac Anesthesia
- Thoracic Surgery
Background:
- Conventional coronary artery bypass grafting (CABG) often involves multiple aortic cross-clamp periods.
- The use of an aortic exclusion clamp can pose risks, especially in patients with severe coronary stenosis or aortic conditions.
- Minimizing aortic manipulation is crucial for reducing perioperative complications.
Purpose of the Study:
- To evaluate the safety and efficacy of a single cross-clamping technique in CABG.
- To compare this technique with conventional methods regarding surgical precision and patient outcomes.
- To assess the applicability of this method in high-risk patients, including those with left main coronary artery stenosis.
Main Methods:
- The study involved 87 consecutive patients undergoing coronary artery operations.
- Hypothermic cardiopulmonary bypass was utilized.
- A single cross-clamping period with multidose infusions of hypothermic cardioplegia was employed for both proximal and distal anastomoses.
Main Results:
- The single cross-clamping technique facilitated precise surgical execution.
- This approach successfully avoided multiple aortic clampings and the associated risk of aortic tear.
- Complete myocardial revascularization was achieved upon clamp release.
Conclusions:
- A single cross-clamping period during CABG is a safe and effective alternative to conventional methods.
- This technique offers advantages in terms of reduced aortic manipulation and potential for fewer complications.
- It is particularly beneficial for patients with severe left main coronary artery stenosis.
Abstract:
Using hypothermic cardiopulmonary bypass and a single cross-clamping period under multidose infusions of hypothermic cardioplegia, both distal and proximal anastomoses were performed in 87 consecutive patients undergoing coronary artery operation. This method allows for precise surgical technique, avoids the need for multiple clampings of the ascending aorta, and appears to avoid the threat of aortic tear. When the clamp is released, the heart has been totally revascularized. This is in contrast to more conventional methods, where an exclusion clamp is applied to the ascending aorta and where the combination of coronary stenosis, low perfusion pressure during bypass, and narrowing of the ascending aorta by the exclusion clamp may be more hazardous than a single cross-clamp period for construction of all anastomoses. This is particularly applicable to patients with severe stenosis of the left main coronary artery.

