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Reiter's keratitis

D B Mark, J B McCulley

    Archives of Ophthalmology (Chicago, Ill. : 1960)
    |May 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Reiter's syndrome can cause distinctive keratitis, often with conjunctivitis and stromal infiltrates. A rare severe case presented with disciform keratitis, potentially linked to Chlamydia infection.

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    Area of Science:

    • Ophthalmology
    • Rheumatology
    • Infectious Diseases

    Background:

    • Reiter's syndrome, a form of reactive arthritis, is frequently associated with ocular manifestations.
    • Keratitis is a common ocular complication, typically presenting with specific clinical features.

    Observation:

    • Three patients with Reiter's keratitis were studied.
    • Two patients exhibited classic signs: conjunctivitis, subepithelial/anterior stromal infiltrates, and epithelial erosions.
    • One patient presented with a rare, severe form of keratitis, including disciform keratitis.

    Findings:

    • The study identified typical and atypical presentations of Reiter's keratitis.
    • Intracytoplasmic inclusions, suggestive of Chlamydia, were observed in corneal cells of one patient.

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  • This patient also showed an elevated serum titer to Chlamydia antigen.

    • Implications:

    • The findings suggest Chlamydia may play a role in the severe keratitis associated with Reiter's syndrome.
    • Disciform keratitis is a newly reported complication of Reiter's syndrome.
    • This highlights the importance of considering infectious etiologies in complex cases of reactive arthritis-related eye disease.