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[Evaluation of pituitary functional periodicity by harmonic analysis. I) Circadian somatotropin secretion in
Abstract:
STH circadian secretion has been investigated in 11 acromegalic patients. The physiological STH nocturnal surge is not present in acromegaly, but when data are evaluated by Fourier's cosines analysis, a rhythmicity is however found also in acromegaly. The characteristics of harmonics, namely periodicity, amplitudes and phases, are largely different in respect to pattern of normal subjects, where the rhythmicity is represented by an harmonics with 24-hour periodicity.