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Atrial fibrillation--a marker for abnormal left ventricular function in coronary heart disease
British Heart Journal
|June 1, 1982
Summary
Atrial fibrillation was found in 0.8% of patients with coronary heart disease. This heart rhythm abnormality significantly correlates with impaired heart function and left ventricular contraction abnormalities.
Area of Science:
- Cardiology
- Cardiac Electrophysiology
Background:
- Coronary heart disease (CHD) is a major cause of morbidity and mortality.
- Atrial fibrillation (AF) is a common arrhythmia, and its relationship with CHD requires further elucidation.
Purpose of the Study:
- To investigate the prevalence of atrial fibrillation in patients with known coronary heart disease.
- To determine the clinical and hemodynamic correlates of atrial fibrillation in this patient population.
Main Methods:
- Retrospective analysis of 1176 patients with known coronary heart disease.
- Cardiac catheterization data was reviewed.
- Comparison between patients with AF and those with sinus rhythm (SR).
Main Results:
- Atrial fibrillation was identified in 10 patients (0.8%) with known coronary heart disease.
- AF significantly correlated with impaired hemodynamic function.
- AF was associated with mitral regurgitation and left ventricular contraction abnormalities.
Conclusions:
- Atrial fibrillation is a potential indicator of underlying myocardial dysfunction in patients with coronary heart disease.
- The presence of AF may signify more extensive cardiac compromise.