Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Zinc, the brain and behavior

C C Pfeiffer, E R Braverman

    Biological Psychiatry
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Zinc is a crucial metal for brain health, essential for nerve function and development. Deficiency can lead to developmental issues and cognitive impairment, but supplementation shows therapeutic potential.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Insurance Companies Fighting the Peer Review Empire without any Validity: the Case for Addiction and Pain Modalities in the face of an American Drug Epidemic.

    SEJ surgery and pain·2018
    Same author

    Quantitative studies on intradermal wheals; pressure required to produce cutaneous wheals.

    Federation proceedings·2010
    Same author

    Quantitative studies on intradermal wheals; the use of a skin plethysmograph to study changes in the volume of cutaneous wheals.

    Federation proceedings·2010
    Same author

    The nociceptive contraction of the musculus cutaneus maximus in the guinea pig as elicited by radiant thermal skin stimulation; temporal and spatial summation and susceptibility to centrally acting analgetic drugs.

    Federation proceedings·2010
    Same author

    The use of local skin temperature responses to evaluate the histamine-like effect of pontocaine (tetracaine, U.S.P.).

    Federation proceedings·2010
    Same author

    The use of the oximeter to study the potency of p-aminophenones as methemoglobin-forming drugs.

    Federation proceedings·2010
    Same journal

    Impact of Transcranial Direct Current Stimulation-Induced Electric Fields on Slowing Cognitive Decline in Older Adults With Mild Cognitive Impairment or Remitted Major Depressive Disorder: An Analysis of the PACt-MD Randomized Clinical Trial.

    Biological psychiatry·2026
    Same journal

    Remembering Jon-Kar Zubieta, M.D., Ph.D.

    Biological psychiatry·2026
    Same journal

    Kappa opioid receptor availability in borderline personality disorder: An in-vivo investigation with [<sup>11</sup>C]EKAP PET imaging.

    Biological psychiatry·2026
    Same journal

    From Satiety to Substance Use: Neural Mechanisms of GLP-1 Signaling in Appetite and Reward.

    Biological psychiatry·2026
    Same journal

    Distinct and Shared Molecular Mechanisms Underlie Morphological-Functional Overcoupling and Undercoupling in Major Depressive Disorder.

    Biological psychiatry·2026
    Same journal

    Dynamic Brain States With Cannabis Intoxication: Beyond "More Is Better" in Interpreting Brain Connectivity.

    Biological psychiatry·2026
    See all related articles

    Area of Science:

    • Neuroscience
    • Human Physiology
    • Biochemistry

    Background:

    • Zinc is the second most abundant metal in the adult human body, concentrated heavily in the brain.
    • High zinc levels are observed in the hippocampus and retina, vital for neural function.
    • Zinc is integral to synaptic transmission, nucleic acid metabolism, and brain tubulin dynamics.

    Purpose of the Study:

    • To highlight the critical role of zinc in brain development and function.
    • To explore the implications of zinc deficiency in neurological disorders.
    • To review the therapeutic applications of zinc in specific brain conditions.

    Main Methods:

    • Literature review of existing studies on zinc's role in the human body.
    • Analysis of research linking zinc levels to brain development and function.

    Related Experiment Videos

  • Examination of clinical data on zinc's efficacy in treating neurological and related disorders.

    • Main Results:

    • Zinc deficiency during development is linked to congenital nervous system abnormalities.
    • Insufficient zinc in children correlates with impaired learning, apathy, and mental retardation.
    • Abnormal zinc levels are associated with alcoholism, schizophrenia, Wilson's disease, and Pick's disease.

    Conclusions:

    • Zinc is indispensable for normal brain development and cognitive function.
    • Zinc homeostasis is critical for preventing and managing various neurological and psychiatric disorders.
    • Zinc supplementation has demonstrated therapeutic benefits for conditions like Wilson's disease and certain types of schizophrenia.