Acute verapamil poisoning: successful treatment with epinephrine

Acute intoxication with verapamil (2400 mg) induced A-V dissociation and circulatory failure in a 38-year-old woman with no previous cardiac disease. Resumption of A-V conduction was observed after administration of orciprenalin, calcium gluconate, and dopamine, with no effect on blood pressure. Epinephrine infusion finally restored satisfactory blood pressure level and allowed a favorable outcome.