Selenium status of thoroughbreds in the United Kingdom

The activity of glutathione peroxidase (GSH-Px) was measured in the erythrocytes of 600 Thoroughbred horses in training; the selenium concentrations in whole blood and serum was measured in over 80 of these Thoroughbreds. A quadratic relationship was demonstrated between erythrocyte GSH-Px and whole blood or serum selenium concentration. There was no significant difference in the activity of aspartate aminotransferase, creatine kinase, or gamma-glutamyl transferase in the serum of Thoroughbreds with high erythrocyte GSH-Px activity (more than 25 u/ml) when compared with those with low erythrocyte GSH-Px activity (less than 15 u/ml).