Frontal lobe meningioma and depression

Area of Science:

• Neurology
• Neuro-oncology
• Geriatric Psychiatry

Background:

• A 61-year-old female patient presented with symptoms of apathetic depression and urinary incontinence.
• These symptoms were initially managed pharmacologically with d-amphetamine.
• The patient was subsequently diagnosed with bilateral frontal lobe meningiomas.

Observation:

• The patient's depression and urinary incontinence showed symptomatic improvement with d-amphetamine treatment.
• The underlying cause was identified as bilateral frontal lobe meningiomas.
• This case highlights a potential link between meningiomas and the observed neurological symptoms.

Findings:

• Amphetamine treatment provided temporary symptomatic relief for depression and incontinence.
• The diagnosis of bilateral frontal lobe meningiomas revealed the causative factor.
• This suggests that amphetamines may offer symptomatic benefits in certain neurological conditions.

Implications:

• This case suggests that amphetamines could potentially be used to manage neurological symptoms in conditions similar to meningiomas.
• Further research is warranted to explore the efficacy and safety of amphetamines in treating neurological deficits caused by brain tumors.
• The findings may inform treatment strategies for patients with similar presentations, potentially improving quality of life.