Related Experiment Video

Updated: Aug 3, 2026

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
09:31

Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry

Published on: March 7, 2019

Cerebral amyloid angiopathy with multiple intracerebral hemorrhages. Case report

K L Tyler, C E Poletti, R C Heros

    Journal of Neurosurgery
    |August 1, 1982
    PubMed

    Insights

    Cerebral amyloid angiopathy (CAA) can cause recurrent intracerebral hemorrhage. Biopsying adjacent brain tissue during hematoma evacuation is recommended for unclear cases.

    Area of Science:

    • Neurology
    • Pathology

    Background:

    • Cerebral amyloid angiopathy (CAA) is linked to neurological disorders, notably atypical dementia.
    • Intracerebral hemorrhage is a significant clinical manifestation of CAA.

    Observation:

    • A 63-year-old patient experienced four intracerebral hemorrhages attributed solely to CAA.
    • This case highlights the potential for recurrent hemorrhages in individuals with CAA.

    Findings:

    • The review emphasizes the pathological features of CAA and its association with intracerebral hemorrhage.
    • CAA-related hemorrhages can occur even without typical predisposing factors.

    Implications:

    • Biopsy of adjacent brain parenchyma is recommended during surgical evacuation of intracerebral hematomas of unknown cause.
    • This approach may aid in diagnosing underlying CAA and managing patient care.

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