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"Pink" diarrhoea: osmotic diarrhoea from a sorbitol-containing vitamin C supplement
Insights
Sorbitol in vitamin C supplements caused prolonged diarrhea in seven children. Doctors recommend dietary changes and sorbitol exclusion for unexplained watery diarrhea in kids.
Area of Science:
- Pediatric Gastroenterology
- Clinical Nutrition
- Toxicology
Background:
- Protracted diarrhea is a common pediatric concern requiring thorough investigation.
- Identifying dietary triggers is crucial for managing chronic gastrointestinal issues in children.
Observation:
- Seven pediatric patients presented with prolonged watery diarrhea.
- Sorbitol, administered via vitamin C supplements, was identified as the causative agent in all cases.
- Pink staining of napkins, linked to cochineal dye in supplements, was noted in five patients.
Findings:
- Sorbitol is a sole cause of protracted diarrhea in susceptible children.
- Vitamin C supplements containing sorbitol and cochineal dye can induce chronic diarrhea and distinctive napkin staining.
- Dietary history is key in diagnosing sorbitol-induced diarrhea.
Implications:
- Clinicians should consider sorbitol in vitamin C supplements when evaluating pediatric chronic diarrhea.
- Excluding sorbitol from the diet is a recommended initial step before extensive diagnostic workups.
- Awareness of hidden sorbitol sources in supplements can prevent unnecessary medical interventions.
Abstract:
Sorbitol was the sole cause of protracted diarrhoea in seven children seen in two paediatric-gastroenterology outpatient departments. The sorbitol had been administered in the form of a vitamin C supplement in all seven children. Pink staining of napkins was a prominent feature in five of these seven patients, and was attributed to the cochineal dye contained in the vitamin C supplement. In children with chronic or intermittent watery diarrhoea, a careful dietary history should be obtained. If sorbitol ingestion is documented, a trial of sorbitol exclusion is recommended before embarking on extensive investigations.
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