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Related Experiment Videos

Diazepam impairs lateral position control in highway driving

J F O'Hanlon, T W Haak, G J Blaauw

    Science (New York, N.Y.)
    |July 2, 1982
    PubMed
    Summary

    Diazepam impairs driving performance, increasing lane variability at higher doses. Even moderate doses may pose risks, suggesting caution with this medication for drivers.

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    Area of Science:

    • Pharmacology
    • Human Factors
    • Traffic Safety

    Background:

    • Driving is a complex psychomotor task.
    • Medications can significantly affect driving ability.
    • Benzodiazepines, like diazepam, are commonly prescribed.

    Purpose of the Study:

    • To investigate the effects of diazepam on driving performance.
    • To assess dose-dependent impairment in expert drivers.

    Main Methods:

    • Nine expert drivers participated in nighttime highway driving tests.
    • Vehicle instrumentation recorded driving parameters.
    • Drivers were administered diazepam (5 and 10 mg), placebo, or no treatment.

    Main Results:

    • 10 mg diazepam significantly increased lateral position variability.
    • Some drivers showed potentially dangerous impairment.
    • No significant impairment was noted at 5 mg compared to placebo.

    Conclusions:

    • Diazepam, particularly at 10 mg, impairs driving skills.
    • Increased lateral variability suggests reduced vehicle control.
    • These findings highlight the risks associated with diazepam use while driving.

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