Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Secretory diarrhea in ulcerative colitis

F K Ghishan, F Mitros, M K Younoszai

    Southern Medical Journal
    |June 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    T Lymphocyte Dynamics in Inflammatory Bowel Diseases: Role of the Microbiome.

    BioMed research international·2015
    Same author

    High vitamin D3 diet administered during active colitis negatively affects bone metabolism in an adoptive T cell transfer model.

    American journal of physiology. Gastrointestinal and liver physiology·2013
    Same author

    NHE3 modulates the severity of colitis in IL-10-deficient mice.

    American journal of physiology. Gastrointestinal and liver physiology·2011
    Same author

    Observations on use of montelukast in pediatric eosinophilic esophagitis: insights for the future.

    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2010
    Same author

    Modulation of neutrophil motility by curcumin: implications for inflammatory bowel disease.

    Inflammatory bowel diseases·2010
    Same author

    Limited effects of dietary curcumin on Th-1 driven colitis in IL-10 deficient mice suggest an IL-10-dependent mechanism of protection.

    American journal of physiology. Gastrointestinal and liver physiology·2008

    Severe secretory diarrhea in a teen was linked to distal ulcerative colitis. The condition resolved after colectomy, suggesting inflammation-driven factors were the cause.

    Area of Science:

    • Gastroenterology
    • Inflammatory Bowel Disease Research

    Background:

    • Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
    • Diarrhea is a common symptom of UC, but secretory diarrhea is less typical.

    Observation:

    • A 15-year-old female presented with severe secretory diarrhea.
    • Her ulcerative colitis was confined to the distal 30 cm of the colon.
    • No other hormonal or pathological cause for the diarrhea was identified.

    Findings:

    • The secretory diarrhea resolved completely following a colectomy.
    • This suggests the diarrhea was secondary to factors within the inflamed distal colon.

    Implications:

    • This case highlights a potential, previously unreported, cause of secretory diarrhea in pediatric ulcerative colitis.

    Related Experiment Videos

  • Further research may explore specific inflammatory mediators responsible for this phenomenon.