Hemodynamics and renal function following experimental suprarenal vena caval occlusion

In this study, the cardiovascular and renal effects of acute suprarenal caval occlusion were investigated in dogs. Marked hemodynamic effects were noted, with an immediate 60 per cent reduction in cardiac output and a 26 per cent drop in mean systemic arterial pressure. In spite of these, there was only a transient disturbance of renal function which had resolved both biochemically and structurally by the end of two weeks. The relevance of these findings to acute occlusion above the renal veins in humans has been reviewed, and we conclude that the Greenfield filter may be inserted in the suprarenal vena cava when indicated with little likelihood of an increase in mortality from recurrent embolism.