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Updated: Aug 15, 2026

Intranasal Administration of Recombinant Influenza Vaccines in Chimeric Mouse Models to Study Mucosal Immunity
Published on: June 25, 2015
[Cellular and humoral immunity studies after vaccination against influenza]
Abstract:
The indices of cellular and humoral immunity (the number of leukocytes, lymphocytes, T- and B cells, E- and EAC-RFC, blastogenic reaction of lymphocytes in response to treatment with phytohemagglutinin and influenza virus antigen in vitro, antihemagglutinin and influenza virus antigen in vitro, antihemmagglutinin titres) in humans vaccinated with different types of inactivated influenza vaccines produced in the USSR and the GDR were investigated. The immunogenic potency, general and immunological innocuity of the inactivated influenza vaccines under study and more marked stimulation of the B-system of immunity by them were demonstrated.
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