[New aspects of chronic occupational manganese poisoning]

Wherever workers are professionally exposed to manganese and its compounds, but particularly in brown haematite mills, a chronic occupational manganese intoxication may appear with the picture of an expressed results of own investigations on 45 workers of a brown haematite mill in Thuringia who were exposed to manganic dust during 11 years as well as on manganese patients who were reported shall contribute to the clarification of the question of early diagnosis and differential diagnosis of a manganese intoxication. Attention is paid to functional diagnostic methods (EEG, EMG). On the basis of successes of treatment with the help of a substitution therapy of L-Dopa and amantine hydro-chloride new aspects concerning the pathogenesis of this disease are reported and conclusions for practice are made.